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Physiological functions of NHR-23

The nhr-23 is required in all larval molts; NHR-23 is highly similar to Drosophila DHR3, an ecdysone-inducible gene product involved in metamorphosis; NHR-23 is required for hypodermal expression of acn-1 and, probably, of dpy-7.

Potential applications of NHR-23

This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules.

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